Creating checkpoints is essential for evaluating the present status, maintaining your project's course, and expediting delivery. This presentation will guide you in establishing appropriate checkpoints for your project/program and enhancing the overall plan for optimization. It will help you analyze the challenges and determine preventive measures for the future and review your plan to consider necessary adjustments or additions.

Study Tracker is an open-source web application that helps research teams organize their projects, connect disparate systems, and automate tedious workflows. Lab Atlas is a managed software-as-a-service version of Study Tracker. This presentation will highlight how these tools can be used to increase productivity and preserve historical records at biotech companies. Learn how Study Tracker and Lab Atlas are used to solve several common problems at biotech companies by doing the following: 1) Tracking all projects & experiments within an organization and linking all the places their data lives; 2) Generating unique, human-readable codes for all experiments that can be used to identify work; 3) Automatically creating ELN folders & entries for experiments, and 4) Creating folders in a managed hierarchy for experimental data and documents in cloud storage systems. 

In this presentation, we explore the power of shared learning and knowledge within the flagship pioneering ecosystem. We delve into how pioneering medicines leverage knowledge management frameworks to simplify digital therapeutic development. We'll discuss the technical implementation of Study Tracker, our research management platform, and demonstrate how integrative collaborations foster an efficient environment for scaling digital therapeutic initiatives, ensuring streamlined, organized project management.

By combining graph databases with Open-Source Full-Stack Technology, companies large and small can be vastly empowered, and no longer at the mercy of juggling proprietary partial solutions, pushed around by vendors whose primary mission is to build walls, rather than dismantle them. Concrete examples will be shared: the modular architecture of the open-source projects BrainAnnex.org and Life123.science.
- NeoAccess: Layer to simplify python interface and common database operations
- NeoSchema: Optional, very flexible, schema
- DataManager: Including full-text indexing
- WebAPI: Flask
- UI: Vue.js  + cytoscape.js ball visualization

UK Biobank is a large-scale cohort study and biomedical database and is one of the world’s most important and widely-used health research resources, containing a wealth of data on genomics, lifestyle factors and health outcomes on half a million participants. Its unique combination of scale, depth, maturity, and accessibility is far ahead of any comparable biological resources (and will remain so for many years to come). As a result, more than 30,000 researchers (10,000 in the US) from around the world are using UK Biobank, with exponential growth in publications and patents now emerging from it. 20 years from its initiation, UK Biobank has surpassed all expectations for its extraordinary impact on increasing understanding of the determinants of disease, identifying factors that can predict future disease risk more accurately and identifying early disease biomarkers. During the next 5 years, UK Biobank would like to increase the depth of characterization of various types of risk factors for disease, and of the many different types of health outcome occurring in participants in order to substantially increase its value for discovery science.

The 20 years since the Human Genome Project have seen transformational advances in molecular understanding of cancers and rare disease, but precision medicine has had limited impact on improving treatment of complex, chronic indications in neuroscience, immune, and inflammatory disorders. To overcome this challenge, we have completely reimagined how to analyze, semantically integrate, and visualize patient and ‘omics data. This approach reveals deeper understanding of disease biology and enables development of diagnostic biomarkers and precision-targeted therapies for chronic diseases that affect billions of people.

We share the story of how our Research Informatics organization came together to reimagine our approach to a drug discovery software product portfolio containing generations of applications built/bought to support decades of research innovation and strategic change. We share how shifting our mindset from projects to products, from applications to capabilities, and from business-aligned silos to a holistic end-to-end drug discovery perspective is enabling and incentivizing modernization, cost-optimization, innovation, and effective delivery on significant new demand.

Replacing a legacy ELN system can be a long and painful process. How about replacing 10 of them together? This presentation will tell the story of Takeda’s multi-year journey to decommission 10 fragmented legacy ELNs, and how a team of ELN implementation experts face the obstacles, and manage technical and organizational challenges to deploy a global integrated SaaS ELN solution to 2,000 R&D scientists.

This talk will be about 30+ years of observations of what not to do and what to do regarding scientific software selection, implementation, and sustainability in biopharma. Examples of successes and failures will be incorporated into the talk for knowledge sharing and learning. The talk will focus on the need for composable environments, collaboration, usability, FAIR (data, processes), extensibility, culture, strategy, assessments, analysis, scientific business process, community, and experience. There will be a lot of information and case studies packed into this 30-minute talk!